Changes in the gamma chain heterogeneity of hemoglobin F of the baboon (Papio cynocephalus) postnatally and after partial switching to hemoglobin F production by various stimuli.

Schroeder WA, DeSimone J, Shelton JB, Shelton JR, Espinueva Z, Hall L, Zwiers D

5-azacytidine for beta thalassaemia?

Ley TJ, Anagnou NP, Young NS, Nienhuis AW, DeSimone J, Heller P

Is increase of fetal hemoglobin due to erythropoietic stress the result of DNA hypomethylation?

DeSimone J, Schimenti JC, Duncan CH, Heller P

Fetal hemoglobin production in adult baboons by 5-azacytidine or by phenylhydrazine-induced hemolysis is associated with hypomethylation of globin gene DNA.

DeSimone J, Heller P, Schimenti JC, Duncan CH

DNA methylation and globin gene expression in patients treated with 5-azacytidine.

Ley TJ, Anagnou NP, Noguchi CT, Schechter AN, DeSimone J, Heller P, Nienhuis AW

5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia.

Ley TJ, DeSimone J, Anagnou NP, Keller GH, Humphries RK, Turner PH, Young NS, Keller P, Nienhuis AW

Maintenance of fetal hemoglobin (HbF) elevations in the baboon by prolonged erythropoietic stress.

DeSimone J, Biel M, Heller P

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.

DeSimone J, Heller P, Hall L, Zwiers D

Detection of Hb-Papio B, a silent mutation of the baboon beta chain, by high performance liquid chromatography. Improved procedures for the separation of globin chains by HPLC.

Shelton JB, Shelton JR, Schroeder WA, DeSimone J

Failure of D-thyroxine to increase fetal hemoglobin levels in normal and anemic baboons.

Koeller D, DeSimone J, Heller P