The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin.

Kachhap SK, Faith D, Qian DZ, Shabbeer S, Galloway NL, Pili R, Denmeade SR, DeMarzo AM, Carducci MA

Preclinical and clinical studies with the multi-kinase inhibitor CEP-701 as treatment for prostate cancer demonstrate the inadequacy of PSA response as a primary endpoint.

Collins C, Carducci MA, Eisenberger MA, Isaacs JT, Partin AW, Pili R, Sinibaldi VJ, Walczak JS, Denmeade SR

Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica.

Liu H, Jensen KG, Tran LM, Chen M, Zhai L, Olsen CE, Søhoel H, Denmeade SR, Isaacs JT, Christensen SB

Phase II evaluation of docetaxel plus exisulind in patients with androgen independent prostate carcinoma.

Sinibaldi VJ, Elza-Brown K, Schmidt J, Eisenberger MA, Rosenbaum E, Denmeade SR, Pili R, Walczak J, Baker SD, Zahurak M, Carducci MA

Synthesis and screening of a random dimeric peptide library using the one-bead-one-dimer combinatorial approach.

Aggarwal S, Harden JL, Denmeade SR

Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.

Janssen S, Rosen DM, Ricklis RM, Dionne CA, Lilja H, Christensen SB, Isaacs JT, Denmeade SR

Anti-tumor effect of combination therapy with intratumoral controlled-release paclitaxel (PACLIMER microspheres) and radiation.

Lapidus RG, Dang W, Rosen DM, Gady AM, Zabelinka Y, O'Meally R, DeWeese TL, Denmeade SR

The impact of usual dietary patterns, selection of significant foods and cuisine choices on changing dietary fat under 'free living' conditions.

Tapsell LC, Hokman A, Sebastiao A, Denmeade S, Martin G, Calvert GD, Jenkins AB

A 5-fluorodeoxyuridine prodrug as targeted therapy for prostate cancer.

Mhaka A, Denmeade SR, Yao W, Isaacs JT, Khan SR

A supramicromolar elevation of intracellular free calcium ([Ca(2+)](i)) is consistently required to induce the execution phase of apoptosis.

Tombal B, Denmeade SR, Gillis JM, Isaacs JT